購(gòu)物車(chē)
幫助
021-54845833/15800441009
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Fusion protein corresponding to C terminal 250 amino acids of human TONSL |
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Full name: |
tonsoku-like, DNA repair protein |
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Synonyms: |
IKBR; NFKBIL2 |
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Swissprot: |
Q96HA7 |
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Gene Accession: |
BC008782 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. |
