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021-54845833/15800441009
中文名稱： CARD9抗原（重組蛋白）
英文名稱： CARD9 Antigen (Recombinant Protein)
別 名： CANDF2; hCARD9
儲 存： 冷凍（-20℃）
相關(guān)類別：抗原
概 述：
|
Fusion protein corresponding to a region derived from 270-481 amino acids of human CARD9 |
技術(shù)規(guī)格：
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Full name: |
caspase recruitment domain family, member 9 |
|
Synonyms: |
CANDF2; hCARD9 |
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Swissprot: |
Q9H257 |
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Gene Accession: |
BC008877 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. |
